DNA and RNA Structure

DNA and RNA Structure

DNA Structure

  • DNA, or deoxyribonucleic acid, is a molecule composed of two long chains of nucleotides that coil around each other to form a double helix.
  • Each nucleotide in a DNA molecule is made up of a deoxyribose sugar, a phosphate group, and one of the four nitrogenous bases: adenine (A), cytosine (C), guanine (G), or thymine (T).
  • Adenine pairs with Thymine and Guanine pairs with Cytosine through hydrogen bonds to form the DNA double helix.
  • DNA is the genetic material that carries information about an organism and is used to pass traits from parent to offspring.

RNA Structure

  • RNA, or ribonucleic acid, is mostly composed of a single strand of nucleotides and uses the same bases as DNA, except it replaces thymine with uracil (U).
  • Each nucleotide in an RNA molecule is made up of a ribose sugar, a phosphate group, and one of the four nitrogenous bases: adenine (A), cytosine (C), guanine (G), or uracil (U).
  • RNA acts as a messenger between DNA and the protein synthesis complexes known as ribosomes, playing a critical role in protein synthesis and sometimes catalysing biological reactions.

DNA to RNA to Protein: Gene Expression

  • Gene expression starts with DNA at the core of the cell. When a certain gene needs to be used, the DNA unwinds and acts as a template for the production of an RNA molecule, in a process known as transcription.
  • The RNA, now containing the complementary sequence to the original DNA strand, leaves the nucleus and goes into the cytoplasm, where it will play a central role in the production of proteins.
  • In the cytoplasm, the RNA molecule is decoded to produce a chain of amino acids which combine to form a protein. This process is known as translation.
  • The protein then folds into a specific shape that determines its function in the organism.

Regulation of Gene Expression

  • The regulation of gene expression refers to the control of the amount and timing of appearance of the functional product of a gene.
  • Regulating gene expression is crucial because it allows an organism to adapt to its changing environment and to carry out the many processes that occur within a cell.
  • Gene regulation can occur at many levels: from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein.

DNA and RNA: Comparison and Contrast

  • Although DNA and RNA both carry genetic material, they are quite different. DNA is double-stranded, while RNA is single-stranded.
  • The bases in DNA are A, T, C, and G, whereas in RNA, T is replaced by U.
  • DNA is responsible for storing and transferring genetic information, while RNA directly codes for amino acids and acts as a messenger between DNA and ribosomes to make proteins.