DNA and RNA Structure
DNA and RNA Structure
DNA Structure
- DNA, or deoxyribonucleic acid, is a molecule composed of two long chains of nucleotides that coil around each other to form a double helix.
- Each nucleotide in a DNA molecule is made up of a deoxyribose sugar, a phosphate group, and one of the four nitrogenous bases: adenine (A), cytosine (C), guanine (G), or thymine (T).
- Adenine pairs with Thymine and Guanine pairs with Cytosine through hydrogen bonds to form the DNA double helix.
- DNA is the genetic material that carries information about an organism and is used to pass traits from parent to offspring.
RNA Structure
- RNA, or ribonucleic acid, is mostly composed of a single strand of nucleotides and uses the same bases as DNA, except it replaces thymine with uracil (U).
- Each nucleotide in an RNA molecule is made up of a ribose sugar, a phosphate group, and one of the four nitrogenous bases: adenine (A), cytosine (C), guanine (G), or uracil (U).
- RNA acts as a messenger between DNA and the protein synthesis complexes known as ribosomes, playing a critical role in protein synthesis and sometimes catalysing biological reactions.
DNA to RNA to Protein: Gene Expression
- Gene expression starts with DNA at the core of the cell. When a certain gene needs to be used, the DNA unwinds and acts as a template for the production of an RNA molecule, in a process known as transcription.
- The RNA, now containing the complementary sequence to the original DNA strand, leaves the nucleus and goes into the cytoplasm, where it will play a central role in the production of proteins.
- In the cytoplasm, the RNA molecule is decoded to produce a chain of amino acids which combine to form a protein. This process is known as translation.
- The protein then folds into a specific shape that determines its function in the organism.
Regulation of Gene Expression
- The regulation of gene expression refers to the control of the amount and timing of appearance of the functional product of a gene.
- Regulating gene expression is crucial because it allows an organism to adapt to its changing environment and to carry out the many processes that occur within a cell.
- Gene regulation can occur at many levels: from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein.
DNA and RNA: Comparison and Contrast
- Although DNA and RNA both carry genetic material, they are quite different. DNA is double-stranded, while RNA is single-stranded.
- The bases in DNA are A, T, C, and G, whereas in RNA, T is replaced by U.
- DNA is responsible for storing and transferring genetic information, while RNA directly codes for amino acids and acts as a messenger between DNA and ribosomes to make proteins.