The Structure of a Nephron

The Structure of a Nephron

  • Nephrons are microscopic tubular structures in the kidneys that philtre waste products from the blood to form urine.
  • Each kidney contains over a million nephrons that work collectively to remove toxic substances from the blood.
  • A nephron consists of two main parts: a renal corpuscle and a renal tubule.
  • The renal corpuscle, located in the renal cortex of the kidney, is composed of the glomerulus, a bundle of capillaries, nested inside Bowman’s capsule.
  • Blood under high pressure is forced into the renal corpuscle where waste products, salt, glucose, and water are filtered from the blood in a process called ultrafiltration.
  • The renal tubule is a long, coiled tube where filtered fluids pass through. It has distinct sections — the proximal convoluted tubule, the loop of Henle, and the distal convoluted tubule.
  • The proximal convoluted tubule (PCT) is where most of the reabsorption occurs, including all the glucose and amino acids, and a large amount of water.
  • The loop of Henle serves to create a concentration gradient in the medulla of the kidney. This helps in the reabsorption of water from the urine.
  • The distal convoluted tubule (DCT) assists in the regulation of potassium, sodium, calcium, and pH levels in the body.
  • The waste product from this process, now called urine, passes through the collecting duct where more water reabsorption can take place depending on the body’s hydration levels.
  • Nephrons play a crucial role in maintaining fluid balance in the body (homeostasis) by adjusting the reabsorption of water and electrolytes.