Inheritance: Sex Determination in Humans

Inheritance: Sex Determination in Humans

  • All humans have 23 pairs of chromosomes in most of their cells- one half inherited from the mother, one half from the father.
  • These include two sex chromosomes, which determine the person’s biological sex.
  • Females have the sex chromosomes XX while males have the sex chromosomes XY.
  • When male sperm cells are formed, each cell either carries an X or a Y sex chromosome.
  • All eggs (female cells) contain one X chromosome.
  • If a sperm cell carrying an X chromosome fertilises the egg, the child will be female (XX).
  • If a sperm cell carrying a Y chromosome fertilises the egg, the child will be male (XY).
  • This means that it is the male sperm that determines the sex of the child.
  • There is a roughly equal chance of a child being male or female, as the sperm carrying either an X or Y chromosome has an equal chance of fertilising the egg.
  • This process is known as sexual reproduction, it is controlled by genes on the sex chromosomes.
  • Sex-linked characteristics, like red-green colour blindness and haemophilia, are carried on the sex chromosomes and so are more often expressed in males. This is because males have a single copy of these genes, while females would need the defective gene to be inherited from both parents.
  • In addition to the simple XY system, variations exist, such as Turner Syndrome (XO) or Klinefelter Syndrome (XXY), which can affect physical development and fertility.