Amines and Amides

Amines and Amides

  • Aliphatic amines are made by reacting ammonia with halogenoalkanes or reducing nitriles.
  • Aromatic amines are created by reducing nitro compounds.
  • Amines are weak bases whose strength depends on the availability of the N lone pair.
  • Key mechanisms include nucleophilic substitution of amines with halogenoalkanes and nucleophilic addition-elimination of amines with acyl chlorides/anhydrides.