Lipids
Characteristics of Lipids
- Lipids are a group of biomolecules that are insoluble in water but soluble in organic solvents.
- They are composed of carbon (C), hydrogen (H) and oxygen (O) atoms, but have a higher proportion of C and H compared to O, making them less polar than carbohydrates or proteins.
- Lipids provide more than twice the energy per gram than carbohydrates or proteins when metabolised.
- They are generally hydrophobic, meaning they do not dissolve in water.
Types of Lipids
- Triglycerides are the main lipids in the diet and body, made up of glycerol and three fatty acids.
- Phospholipids have a similar structure to triglycerides but one fatty acid is replaced by a phosphate group. They are crucial in forming cell membranes.
- Sterols or steroids, such as cholesterol, play roles in cellular structure and certain hormones.
- Waxes are long-chain fatty acids linked to long-chain alcohols, providing protection and waterproofing in plants and animals.
Role of Lipids in the Body
- Lipids are a major store of energy in the body, with fat cells being specially adapted for this purpose.
- They are important for insulation and protection. Subcutaneous fat helps to maintain body temperature and around internal organs, fatty tissue provides cushioning to protect against damage.
- Lipids are key in making up cell membranes, contributing to membrane fluidity and facilitating the transport of certain substances.
- Certain lipids play a crucial role in the production of hormones, which regulate many body functions like metabolism and immune response.
- Lipids, such as cholesterol, are necessary for the synthesis of vitamin D and bile salts.
Lipid Metabolism
- Digestion breaks down dietary lipids into fatty acids and monoglycerides that can be absorbed by the cells of the small intestine.
- Once absorbed, these components are reassembled into triglycerides and packaged with proteins and phospholipids into chylomicrons for transport in the blood.
- Excess dietary lipids not immediately used for energy are stored as body fat.
- When energy is needed, stored lipids are broken down through lipolysis into usable forms.
- Lipids can also be synthesised in the body from excess dietary carbohydrates or proteins through a process called lipogenesis.
Lipids in Diet and Health
- The types and amounts of lipids in the diet can greatly influence health.
- Saturated fats, found in animal products and tropical oils, can raise levels of LDL cholesterol and potentially contribute to heart disease when consumed in excess.
- Unsaturated fats, found in plants and fish, can lower LDL cholesterol levels and are a necessary part of the diet.
- Trans fats, present in some processed foods, raise LDL cholesterol and also lower beneficial HDL cholesterol, and are associated with an increased risk of heart disease.